We examined the relationship between vitamin C intake and the risk of developing kidney stones in a large cohort. This study included a significant number of participants: 156,735 women from the Nurses' Health Studies and 40,536 men from the Health Professionals Follow-up Study.
Our findings revealed that total and supplemental vitamin C intake was linked to a higher risk of kidney stones in men, but there was no such association evident in women. Specifically, among men, those who consumed higher amounts of vitamin C had greater likelihoods of developing stones when compared to those with lower intakes.
However, dietary vitamin C did not show a connection with kidney stones in either men or women. This suggests that while supplements may pose risks for men, dietary sources of vitamin C might not have the same impact. Overall, the study indicates that we should be cautious about high vitamin C supplement consumption, especially for men, while highlighting that dietary intake appears safe.
Read More
9.5
No connection between IVC and stones
No Reported Renal Stones with Intravenous Vitamin C Administration: A Prospective Case Series Study.
We set out to investigate whether high doses of intravenous vitamin C (IVC) could influence the formation of kidney stones. Our study involved 157 adult patients receiving IVC therapy at Integrated Health Options clinic over a 12-month period.
Throughout the study, we conducted regular check-ins with patients, specifically asking about any kidney stones they might have experienced, along with monitoring their renal function through blood tests. Despite some patients having a prior history of kidney stones, we found that none reported developing new stones during the study.
Interestingly, we also noted that the majority of participants showed stable renal function, as indicated by consistent serum creatinine levels and estimated glomerular filtration rates (eGFR). In summary, our findings suggest that IVC therapy does not appear to be associated with an increased risk of kidney stones.
Read More
8
Vitamin C may reduce kidney stones
Evaluating the American Urologic Association (AUA) dietary recommendations for kidney stone management using the National Health And Nutritional Examination Survey (NHANES).
We explored the dietary habits of individuals from the National Health and Nutritional Examination Survey (NHANES) to see how certain foods might influence kidney stone formation.
Our focus was particularly on vitamin C and its potential role in preventing these painful stones. We looked at a diverse group of nearly 17,000 people, analyzing their dietary intake alongside their kidney health over a span of several years.
Interestingly, our findings highlighted a connection between higher vitamin C intake and reduced kidney stone risk. Specifically, we noted that individuals consuming 60 to 110 mg of vitamin C daily had a lower chance of forming stones, with an even greater protective effect observed in those exceeding that amount.
While we didn't find significant associations with many other dietary elements, our results suggest that increasing vitamin C intake might be beneficial. This points towards a need for further research on how vitamin C and other dietary factors interact in the context of kidney stone prevention.
Read More
Most Useful Reviews
9
No kidney stones
4 people found this helpful
Great, easily absorbable Vitamin C that doesn't cause kidney stones! I have metabolism issues and am unable to process many synthetic vitamins. This product is one of the few I can take without the risk of kidney stones or detox problems. Its dosage is higher than others, making it more affordable. A fantastic option for those needing a natural, absorbable Vitamin C.
Read More
0
Caused kidney pain
1 people found this helpful
I experienced kidney pain after using this product; however, the pain eased once I stopped taking it.
Read More
9
Gentle on kidneys
This is the best Vitamin C available. Unlike ascorbic acid, it is gentle on the kidneys and does not cause discomfort.
We set out to investigate whether high doses of intravenous vitamin C (IVC) could influence the formation of kidney stones. Our study involved 157 adult patients receiving IVC therapy at Integrated Health Options clinic over a 12-month period.
Throughout the study, we conducted regular check-ins with patients, specifically asking about any kidney stones they might have experienced, along with monitoring their renal function through blood tests. Despite some patients having a prior history of kidney stones, we found that none reported developing new stones during the study.
Interestingly, we also noted that the majority of participants showed stable renal function, as indicated by consistent serum creatinine levels and estimated glomerular filtration rates (eGFR). In summary, our findings suggest that IVC therapy does not appear to be associated with an increased risk of kidney stones.
Read More
8
CDAI may reduce kidney stones
High composite dietary antioxidant index is associated with reduced risk of kidney stones: a cross-sectional analysis of NHANES 2007-2020.
We examined the relationship between dietary antioxidant intake, particularly vitamin C, and the risk of developing kidney stones. Utilizing data from the National Health and Nutrition Examination Survey, we found that individuals with higher levels of antioxidants, as indicated by the Composite Dietary Antioxidant Index (CDAI), had lower odds of forming kidney stones.
Stone formers, those who have experienced kidney stones, typically had a lower CDAI, showcasing significant differences based on gender. An interesting aspect of our findings was that vitamin C stood out as having the strongest negative correlation with kidney stones, suggesting that increased intake may be beneficial.
The results indicated that those in moderate and high CDAI groups had reduced odds of experiencing kidney stones compared to the lowest group. This was reflected in the odds ratios, which showed a significant decrease for those with higher antioxidant consumption. Therefore, it seems that a diet rich in antioxidants, particularly vitamin C, could play a role in lowering kidney stone risks.
However, while our findings are promising, we emphasize the need for more in-depth cohort studies to further investigate this potential connection and confirm its causal nature.
Read More
8
Vitamin C may reduce kidney stones
Evaluating the American Urologic Association (AUA) dietary recommendations for kidney stone management using the National Health And Nutritional Examination Survey (NHANES).
We explored the dietary habits of individuals from the National Health and Nutritional Examination Survey (NHANES) to see how certain foods might influence kidney stone formation.
Our focus was particularly on vitamin C and its potential role in preventing these painful stones. We looked at a diverse group of nearly 17,000 people, analyzing their dietary intake alongside their kidney health over a span of several years.
Interestingly, our findings highlighted a connection between higher vitamin C intake and reduced kidney stone risk. Specifically, we noted that individuals consuming 60 to 110 mg of vitamin C daily had a lower chance of forming stones, with an even greater protective effect observed in those exceeding that amount.
While we didn't find significant associations with many other dietary elements, our results suggest that increasing vitamin C intake might be beneficial. This points towards a need for further research on how vitamin C and other dietary factors interact in the context of kidney stone prevention.
Read More
8
Vitamin C formulation lowers oxalate
Vitamin C with metabolites reduce oxalate levels compared to ascorbic acid: a preliminary and novel clinical urologic finding.
We examined how different forms of vitamin C affect kidney stones, specifically looking at hyperoxaluria, a key risk factor for stone formation. In our study, conducted as a randomized, double-blind, crossover trial, we compared the effects of traditional ascorbic acid with a formulation containing vitamin C and metabolites, known as Ester-C.
Our findings revealed that Ester-C significantly lowered urine oxalate levels compared to regular ascorbic acid. This is exciting because higher oxalate levels in urine can lead to kidney stones, and finding a formulation that mitigates this risk is important.
Although this study presents promising results, it's essential to note that further evaluation is necessary to fully understand these findings. We believe this is a novel insight into the potential of vitamin C to help prevent kidney stones, and we look forward to additional research in this area.
Read More
7
Vitamin C's complex impact revealed
Multivitamins co-intake can reduce the prevalence of kidney stones: a large-scale cross-sectional study.
We sought to understand how varying levels of vitamin C, among other vitamins, affect the prevalence of kidney stones. Our research relied on comprehensive data from NHANES, which allowed us to evaluate the relationships between nine common vitamins and kidney stone conditions.
Through logistic regression and detailed cluster analysis, we discovered that high vitamin C intake can have a complex impact. While individuals with very high vitamin B6 and D levels showed a decrease in kidney stone issues, vitamin C presented a different picture. Initially, as vitamin C intake increased, the risk for kidney stones seemed to drop. However, after a certain threshold, that benefit waned, and we observed a potential increase in risk instead.
This means that while vitamin C can be beneficial in moderation, too much might not be the best for kidney health. Furthermore, we found that when combined with other vitamins, particularly in specific patterns, the protective effects against kidney stones enhanced, suggesting that overall dietary balance is crucial.
Our findings shed light on a nuanced relationship between vitamin C and kidney stones, emphasizing the importance of considering not just individual vitamins, but how they work together.
Great, easily absorbable Vitamin C that doesn't cause kidney stones! I have metabolism issues and am unable to process many synthetic vitamins. This product is one of the few I can take without the risk of kidney stones or detox problems. Its dosage is higher than others, making it more affordable. A fantastic option for those needing a natural, absorbable Vitamin C.
Read More
0
Caused kidney pain
1 people found this helpful
I experienced kidney pain after using this product; however, the pain eased once I stopped taking it.
Read More
9
Gentle on kidneys
This is the best Vitamin C available. Unlike ascorbic acid, it is gentle on the kidneys and does not cause discomfort.
Read More
7.5
Health improvement
1 people found this helpful
My husband has kidney problems, and after two weeks of use, his health is improving. I will definitely buy this again.
Read More
7.5
Less kidney strain
This Vitamin C appears to be easier on the kidneys and also includes bioflavonoids. Top quality!
Kidney stones are hard deposits made of minerals and salts that form inside your kidneys. While they can vary in size from tiny particles to large stones, they all begin as crystallized substances that develop when urine contains more crystal-forming substances than the fluid in your urine can dilute. When the crystals stick together, they can form stones, which may cause severe pain, especially when they pass through the urinary tract. Common types of kidney stones include calcium stones, struvite stones, uric acid stones, and cystine stones.
The symptoms of kidney stones can include sharp pain in the side and back, pain during urination, pink or red urine, and frequent urination. Various factors can increase the risk of developing kidney stones, including dehydration, certain dietary choices, and genetic predisposition. Preventing kidney stones often involves drinking plenty of water, avoiding excessive salt and animal protein, and ensuring a balanced intake of calcium. For those who suffer from kidney stones, a medical evaluation may be necessary to determine the best management and preventive strategies.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a critical role in numerous bodily functions. As an essential nutrient, it contributes to the growth and repair of tissues in the body, and it is vital for the production of collagen, an important protein that helps maintain skin, cartilage, tendons, ligaments, and blood vessels. Additionally, Vitamin C acts as a powerful antioxidant, which means it helps combat free radicals—unstable molecules that can cause oxidative stress and contribute to various chronic diseases.
Moreover, Vitamin C enhances iron absorption from plant-based foods, making it a vital component for those following vegetarian or vegan diets. While many people get sufficient Vitamin C from a well-balanced diet that includes fruits and vegetables like oranges, strawberries, kiwi, broccoli, and bell peppers, some individuals might require supplementation. It's generally recommended to stay within the daily intake guidelines, as excessive consumption can lead to gastrointestinal disturbances. Overall, Vitamin C is not just a skincare celebrity—it's a fundamental part of maintaining overall health and well-being.
Based on user reviews, the time frame to see results from the Vitamin C supplement for kidney stones varies among individuals. Some users have reported noticeable improvements in as little as two weeks, stating that their health began to improve after consistent use of the supplement Read Review. Other reviewers emphasized that the supplement is gentle on the kidneys, which could imply that even if symptoms are alleviated quickly, the overall benefit may take some time to fully manifest Read Review.
It's important to note that while some users experienced kidney pain that subsided after discontinuing the product Read Review, others found it beneficial without negative side effects Read Review. Thus, individual results may vary greatly, and it might be valuable to monitor your own response closely over a couple of weeks.
Scientific research indicates that vitamin C may play a complex role in the prevention and risk of kidney stones. A study examining antioxidant intake highlighted that individuals with higher vitamin C consumption had lower odds of developing stones, showcasing the potential protective benefits of this vitamin [1]. However, other research has suggested a nuanced relationship; while moderate intake of vitamin C seems beneficial, excessive intake might increase the risk, particularly for men [2], [6].
Moreover, observational studies suggest that dietary sources of vitamin C do not correlate with increased risk, contrasting with higher supplemental doses that can be problematic for men [6]. Interestingly, intravenous vitamin C did not lead to new stone formation in patients undergoing treatment [5]. This indicates that while vitamin C can possibly aid in reducing kidney stone risks through dietary means, caution should be exercised with high supplemental doses, particularly for men. Overall, while the current body of research supports a beneficial role of vitamin C in kidney stone risk reduction under specific conditions, further studies are necessary for a comprehensive understanding.
Users have reported a range of improvements in symptoms after using this Vitamin C supplement, particularly in relation to kidney health. Several reviewers noted that the supplement is gentle on the kidneys and does not cause discomfort, which contrasts with other forms of Vitamin C that led to issues such as kidney pain. For instance, one user mentioned that after two weeks of use, their husband's kidney health showed signs of improvement, highlighting positive outcomes for those with pre-existing kidney problems Read Review. Another user echoed this sentiment, suggesting that the product's formulation is effective and well-tolerated for those who might have difficulty processing synthetic vitamins Read Review.
Additionally, some reviewers emphasized the affective absorption of this Vitamin C compared to synthetic alternatives. They found it to be easier on the kidneys and beneficial for detoxification processes Read Review. While most experiences appear positive, one user did report kidney pain that subsided after they stopped using the product, underlining the importance of monitoring individual responses when trying out new supplements Read Review. Overall, while many users have reported favorable results, individual experiences may vary widely.
Based on user reviews, many individuals have reported positive experiences with combining this Vitamin C supplement with their existing regimen for managing kidney health. Users have highlighted that this formulation is gentle on the kidneys, making it suitable for those who may have difficulties with synthetic supplements. For instance, one reviewer noted that this Vitamin C does not cause kidney stones and is a great option for those with metabolism issues who struggle to process many other vitamins Read Review. Another user emphasized that this product is not only easier on the kidneys but also includes beneficial bioflavonoids, enhancing its overall quality Read Review.
However, it’s worth mentioning that while most feedback is positive, experiences can vary significantly among users. One reviewer reported experiencing kidney pain after use, although this discomfort ceased once they stopped taking the supplement Read Review. Moreover, some users noted improvements in kidney health while using this Vitamin C regularly, suggesting it may be a complementary addition for those already managing kidney issues Read Review. This indicates a generally favorable response to the supplement when used alongside other health strategies.
Research suggests that an optimal daily intake of vitamin C for treating or preventing kidney stones falls within the range of 60 to 110 mg. Studies indicate that individuals consuming this amount tended to have a lower chance of forming kidney stones. Moreover, a protective effect was noted for those exceeding this intake level as well [3]. However, it’s important to approach vitamin C consumption with caution.
High doses over a certain threshold may actually reverse the beneficial effects, leading to an increased risk of stones [2]. In particular, data indicates that men may be more susceptible to kidney stone formation at high supplemental doses (between 250 to 1499 mg), while dietary sources of vitamin C do not show a similar correlation [6]. Therefore, moderation appears key, and individuals should consider achieving their vitamin C intake through a balanced diet rather than high-dose supplements for the best kidney health outcomes.
7.5
Health improvement
1 people found this helpful
My husband has kidney problems, and after two weeks of use, his health is improving. I will definitely buy this again.
9
Gentle on kidneys
This is the best Vitamin C available. Unlike ascorbic acid, it is gentle on the kidneys and does not cause discomfort.
0
Caused kidney pain
1 people found this helpful
I experienced kidney pain after using this product; however, the pain eased once I stopped taking it.
9
No kidney stones
4 people found this helpful
Great, easily absorbable Vitamin C that doesn't cause kidney stones! I have metabolism issues and am unable to process many synthetic vitamins. This product is one of the few I can take without the risk of kidney stones or detox problems. Its dosage is higher than others, making it more affordable. A fantastic option for those needing a natural, absorbable Vitamin C.
6
Kidney-friendly vitamin
Concentrated Vitamin C is completely natural. It is absorbed more slowly than synthetic forms but is gentler on the kidneys and aids in excretion.
7.5
Less kidney strain
This Vitamin C appears to be easier on the kidneys and also includes bioflavonoids. Top quality!
8
CDAI may reduce kidney stones
High composite dietary antioxidant index is associated with reduced risk of kidney stones: a cross-sectional analysis of NHANES 2007-2020.
We examined the relationship between dietary antioxidant intake, particularly vitamin C, and the risk of developing kidney stones. Utilizing data from the National Health and Nutrition Examination Survey, we found that individuals with higher levels of antioxidants, as indicated by the Composite Dietary Antioxidant Index (CDAI), had lower odds of forming kidney stones.
Stone formers, those who have experienced kidney stones, typically had a lower CDAI, showcasing significant differences based on gender. An interesting aspect of our findings was that vitamin C stood out as having the strongest negative correlation with kidney stones, suggesting that increased intake may be beneficial.
The results indicated that those in moderate and high CDAI groups had reduced odds of experiencing kidney stones compared to the lowest group. This was reflected in the odds ratios, which showed a significant decrease for those with higher antioxidant consumption. Therefore, it seems that a diet rich in antioxidants, particularly vitamin C, could play a role in lowering kidney stone risks.
However, while our findings are promising, we emphasize the need for more in-depth cohort studies to further investigate this potential connection and confirm its causal nature.
7
Vitamin C's complex impact revealed
Multivitamins co-intake can reduce the prevalence of kidney stones: a large-scale cross-sectional study.
We sought to understand how varying levels of vitamin C, among other vitamins, affect the prevalence of kidney stones. Our research relied on comprehensive data from NHANES, which allowed us to evaluate the relationships between nine common vitamins and kidney stone conditions.
Through logistic regression and detailed cluster analysis, we discovered that high vitamin C intake can have a complex impact. While individuals with very high vitamin B6 and D levels showed a decrease in kidney stone issues, vitamin C presented a different picture. Initially, as vitamin C intake increased, the risk for kidney stones seemed to drop. However, after a certain threshold, that benefit waned, and we observed a potential increase in risk instead.
This means that while vitamin C can be beneficial in moderation, too much might not be the best for kidney health. Furthermore, we found that when combined with other vitamins, particularly in specific patterns, the protective effects against kidney stones enhanced, suggesting that overall dietary balance is crucial.
Our findings shed light on a nuanced relationship between vitamin C and kidney stones, emphasizing the importance of considering not just individual vitamins, but how they work together.
4
Vitamin C intake risks explored
Total, Dietary, and Supplemental Vitamin C Intake and Risk of Incident Kidney Stones.
We examined the relationship between vitamin C intake and the risk of developing kidney stones in a large cohort. This study included a significant number of participants: 156,735 women from the Nurses' Health Studies and 40,536 men from the Health Professionals Follow-up Study.
Our findings revealed that total and supplemental vitamin C intake was linked to a higher risk of kidney stones in men, but there was no such association evident in women. Specifically, among men, those who consumed higher amounts of vitamin C had greater likelihoods of developing stones when compared to those with lower intakes.
However, dietary vitamin C did not show a connection with kidney stones in either men or women. This suggests that while supplements may pose risks for men, dietary sources of vitamin C might not have the same impact. Overall, the study indicates that we should be cautious about high vitamin C supplement consumption, especially for men, while highlighting that dietary intake appears safe.
9.5
No connection between IVC and stones
No Reported Renal Stones with Intravenous Vitamin C Administration: A Prospective Case Series Study.
We set out to investigate whether high doses of intravenous vitamin C (IVC) could influence the formation of kidney stones. Our study involved 157 adult patients receiving IVC therapy at Integrated Health Options clinic over a 12-month period.
Throughout the study, we conducted regular check-ins with patients, specifically asking about any kidney stones they might have experienced, along with monitoring their renal function through blood tests. Despite some patients having a prior history of kidney stones, we found that none reported developing new stones during the study.
Interestingly, we also noted that the majority of participants showed stable renal function, as indicated by consistent serum creatinine levels and estimated glomerular filtration rates (eGFR). In summary, our findings suggest that IVC therapy does not appear to be associated with an increased risk of kidney stones.
8
Vitamin C may reduce kidney stones
Evaluating the American Urologic Association (AUA) dietary recommendations for kidney stone management using the National Health And Nutritional Examination Survey (NHANES).
We explored the dietary habits of individuals from the National Health and Nutritional Examination Survey (NHANES) to see how certain foods might influence kidney stone formation.
Our focus was particularly on vitamin C and its potential role in preventing these painful stones. We looked at a diverse group of nearly 17,000 people, analyzing their dietary intake alongside their kidney health over a span of several years.
Interestingly, our findings highlighted a connection between higher vitamin C intake and reduced kidney stone risk. Specifically, we noted that individuals consuming 60 to 110 mg of vitamin C daily had a lower chance of forming stones, with an even greater protective effect observed in those exceeding that amount.
While we didn't find significant associations with many other dietary elements, our results suggest that increasing vitamin C intake might be beneficial. This points towards a need for further research on how vitamin C and other dietary factors interact in the context of kidney stone prevention.
References
Huang A, Huang W, Ye Y, Liu L, Wang H, et al. High composite dietary antioxidant index is associated with reduced risk of kidney stones: a cross-sectional analysis of NHANES 2007-2020. Nutr Res. 2024;128:60. doi:10.1016/j.nutres.2024.06.006
Zeng H, Liu Z, He Y, Chen H, He J, et al. Multivitamins co-intake can reduce the prevalence of kidney stones: a large-scale cross-sectional study. Int Urol Nephrol. 2024;56:2991. doi:10.1007/s11255-024-04021-9
Liu Kot K, Labagnara K, Kim JI, Loloi J, Gupta K, et al. Evaluating the American Urologic Association (AUA) dietary recommendations for kidney stone management using the National Health And Nutritional Examination Survey (NHANES). Urolithiasis. 2023;51:60. doi:10.1007/s00240-023-01423-9
Jiang K, Tang K, Liu H, Xu H, Ye Z, et al. Ascorbic Acid Supplements and Kidney Stones Incidence Among Men and Women: A systematic review and meta-analysis. Urol J. 2019;16:115. doi:10.22037/uj.v0i0.4275
Prier M, Carr AC, Baillie N. No Reported Renal Stones with Intravenous Vitamin C Administration: A Prospective Case Series Study. Antioxidants (Basel). 2018;7. doi:10.3390/antiox7050068
Ferraro PM, Curhan GC, Gambaro G, Taylor EN. Total, Dietary, and Supplemental Vitamin C Intake and Risk of Incident Kidney Stones. Am J Kidney Dis. 2016;67:400. doi:10.1053/j.ajkd.2015.09.005
Modi J, Modi P, Pal B, Bansal J, Kumar S, et al. Role of Vitamin C and E supplementation in reduction of serum level of renal injury marker following shock wave lithotripsy: Prospective single centre experience. Urol Ann. 2015;7:350. doi:10.4103/0974-7796.156143
Moyad MA, Combs MA, Crowley DC, Baisley JE, Sharma P, et al. Vitamin C with metabolites reduce oxalate levels compared to ascorbic acid: a preliminary and novel clinical urologic finding. Urol Nurs. 2009;29:95.